Mary Jane De Souza
Ph.D., 1988, Exercise Physiology,
University
of Connecticut
Professor of Kinesiology
Contact Information
104 Noll Laboratory
The Pennsylvania State University
University Park, PA 16802
(814) 863-0045
Fax: (814) 865-4602
mjd34@psu.edu
“REFUEL” Active Women’s Study II
Research Interests
Women's health and Physical Activity,
Endocrinology of the Female Athlete,
Effects of Exercise on the Menstrual Cycle,
Female Athlete Triad (Eating disorders, amenorrhea and osteoporosis),
Eating Behaviors, Food Intake, and Exercise, Luteal Phase Defects and Amenorrhea,
Bone Health and Osteoporosis in Female Athletes, and Energy Deficiency and Bone Health
Selected Publications
Vescovi, J., S Jamal, MJ De Souza. Strategies to Reverse Bone Loss in Women with Functional Hypothalamic Amenorrhea: A Systematic Review of the Literature. Osteoporosis International. 2008 Jan 8; [Epub ahead of print].
Vescovi, J., JL VanHeest, MJ De Souza. Short term response of bone turnover to low dose oral contraceptives in exercising women with hypothalamic amenorrhea. Contraception. 2008 Feb; 77( 2): 97-104. Epub 2007 Dec 21.
Vescovi, J., JL Scheid, R Hontscharuk, MJ De Souza. Dietary Restraint: Impact on Bone, Menstrual and Metabolic Status in Young Women. Physiology and Behaviour. Submitted: 09/2007.
O’Donnell, E., PJ. Harvey, MJ De Souza.Increased Vascular Resistance in Amenorrheic Exercising Women is Associated with Energy Deficiency but not with Increased Inflammation or Oxidative Stress. Journal of Applied Physiology. Submitted: 09/2007.
SL West, JL Scheid, NI Williams, MJ De Souza . Evidence of Elevated Osteoprotegerin Levels in Exercising Women with Hypothalamic Amenorrhea. Bone. Submitted 10/2007.
Scheid, J.L., N.I. Williams, S.L. West., MJ De Souza. Elevated PYY is Associated with Energy Deficiency and Indices of Subclinical Disordered Eating in Exercising Women with Hypothalamic Amenorrhea. American Journal of Clinical Nutrition. Submitted: 10/2007.
De Souza, MJ, S West, S. Jamal, G Hawker and NI Williams. Energy Deficiency and Estrogen Deficiency are associated with Uncoupling of Bone Turnover in Exercising Women. Bone. Submitted: 08/2007.
Loucks , AB , MJ De Souza , NI Williams. Lifetime Exercise and In Vitro Fertilization. Obstetrics and Gynecology. 2007, Feb;109 (2 Pt 1):456-7.
O’Donnell, E., P. Harvey, J. Goodman, De Souza, MJ. Long Term Estrogen Deficiency Lowers Regional Blood Flow, Resting Systolic Blood Pressure and Heart Rate in Exercising Premenopausal Women. American Journal of Physiology: Endocrinology and Metabolism. 2007 May;292(5):E1401-9. Epub 2007 Jan 16.
De Souza, MJ , NI Williams, J Alleyne, JD Vescovi, JL VanHeest, MP Warren. Correction of Misinterpretations and Misrepresentations of the Female Athlete Triad. British Journal of Sports Medicine. 2007 Jan;41(1):58-9 .
De Souza, MJ, DK Lee, JL VanHeest, J Scheid, S West, NI Williams. Severity of energy-related menstrual disturbances increases in proportion to indices of energy conservation in exercising women. Fertility and Sterility. 2007, Oct;88(4):971-5, Apr 4; [Epub ahead of print].
De Souza, MJ, R Hontscharuk, M Olmsted, T Burke, G Kerr, NI Williams. Drive for Thinness Score is a Proxy Indicator of Energy Deficiency in Exercising Women. Appetite. 2007 May;48(3):359-67, 2006 Dec 20 [Epub ahead of print].
Williams, NIand MJDe Souza. Female Athlete Triad Errors and Misunderstandings. Medicine and Science in Sports and Exercise, 2006, 38(5): 3-5.
Thompson, HS, SP Scordilis, and MJ De Souza. Estrogen, progesterone and exercise modulate sarcolemmal permeability in premenopausal women. Hormone Research. 2006;65:151-158.
Kerr, G, E Berman and MJ De Souza. Disordered Eating in Gymnasts: Perspectives of Athletics, Coaches and Parents. Journal of Applied Sports Psychology. 2006, 18(1):28-43.
Berman, E, G Kerr and M.J. De Souza. A Qualitative Exploration of Weight Concerns,
Eating and Exercise Behaviors in Recreational Exercisers. Women in Sport and Physical Activity Journal. 14 (1):24-38, 2005.
LE Armstrong, CM Maresh, TA Elliott, N Keith, JL VanHeest, TP Scheett, J Stoppani, DA Judelson,and MJ De Souza. Heat Acclimation and Physical Training Adaptations of Young Women Using Different Contraceptive Hormones. American Journal of Physiology: Endocrinology and Metabolism. 2005, 288(5):E868-75, 2004 Dec 14; [Epub ahead of print].
De Souza, MJ and NI Williams. Beyond Hypoestrogenism in Amenorrheic Athletes:
Energy Deficiency as a Contributing Factor for Bone Loss. Current Sports Medicine Reports. 2005, 4(1):38-44.
De Souza, MJ and NI Williams. Physiological Aspects and Clinical Sequelae of Energy Deficiency and Hypoestrogenism in Exercising Women. Human Reproduction Update, 2004, 10(5):433-448.
De Souza, MJ, H McConnell, E O’Donnell, B Lasley, and NI Williams. Fasting Ghrelin Levels in Physically Active Women: Relationship with Menstrual Disturbances and Metabolic Status. Journal of Clinical Endocrinology and Metabolism. 2004, 89(7):3536-3542.
E O’Donnell, and De Souza, MJ. The Cardiovascular Effects of Chronic Hypoestrogenism in Amenorrheic Athletes: A Critical Review. Sports Medicine. 2004, 34(9):601-627.
De Souza, MJ. Menstrual Disturbances in Athletes: A Focus on Luteal Phase Defects. Medicine and Science in Sport and Exercise. 2003, 35(9), 1553-1563.
De Souza, MJ, JP VanHeest, L Demers, and B Lasley. Luteal Phase Deficiency in Recreational Runners: Evidence for a Hypometabolic State. Journal of Clinical Endocrinology and Metabolism. 2003, 88 (1), 337-346.
Klentrou, P, M Cunliffe, J Slack, B Wilk, O Bar-O, MJ De Souza, and M Plyley. Temperature Regulation during Rest and Exercise in the Cold in Premenarcheal and Menarcheal Girls. Journal of Applied Physiology. 2003, 96(4):1393-1398.
De Souza, MJ , BE Miller, LS Pescatello, AA Luciano, AB Loucks, and B Lasley. High Frequency of Luteal Phase Deficiency and Anovulation in Female Recreational Runners: Blunted Elevation in FSH Observed During Luteal-Follicular Transition. Journal of Clinical Endocrinology and Metabolism, 1998, 83 (12): 4220-4232.