W. Larry Kenney

 W. Kenney

Professor of Physiology and Kinesiology

Contact Information

102 Noll Laboratory
The Pennsylvania State University
University Park PA 16802


(fax) 814-865-4602





Ph.D., 1983, Physiology, Penn State University

Research Interests

Human temperature regulation focusing on cardiovascular responses to exercise and passive thermal stress; biophysics of heat exchange between humans and the environment.


  • Control of human skin blood flow with an emphasis on aging.
  • Physiology and biophysics of heat exchange between humans and the environment.
  • Thermoregulation during exercise and in extreme environments.

Selected Publications

Simmons, G.H., B.J. Wong, L.A. Holowatz, and W.L. Kenney. Changes in the control of skin blood flow with exercise training: where do cutaneous vascular adaptations fit in? Experimental Physiology 96:822-828, 2011.

Holowatz, L.A. and W.L. Kenney. Oral atorvastatin therapy increases nitric oxide-dependent cutaneous vasodilation in humans by decreasing ascorbate-sensitive oxidants. American Journal of Physiology 301:R763-R768, 2011.

Holowatz, L.A. and W.L. Kenney. Acute localized administration of tetrahydrobiopterin and systemic atorvastatin restore cutaneous microvascular function in hypercholesterolaemic humans. Journal of Physiology 589:4787-4797, 2011.

Stanhewicz, A.E., R.S. Bruning, C.J. Smith, W.L. Kenney, and L.A. Holowatz. Local tetrahydrobiopterin administration augments reflex cutaneous vasodilatation through nitric oxide-dependent mechanisms in aged human skin. Journal of Physiology 112:791-797, 2012.

Bruning, R.S., L. Santhanam, A.E. Stanhewicz, C.J. Smith, D.E. Berkowitz, W.L. Kenney, and L.A. Holowatz. Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin. Journal of Applied Physiology 112:2019-2026, 2012.

Strategic Themes

  • Domains of Health and Behavior